Search Results - alex+chapman

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Helix-grafted Proteins as Inhibitors of Disease-relevant Protein-protein Interactions Helix Grafted Proteins Inhibition of HIV-1 InfectionInventors:Brian R McNaughtonAlan J KennanSusanne N WalkerRachel L TennysonAlex M ChapmanAt a GlanceMcNaughton et al. engineered helix-grafted scaffolds capable of inhibiting HIV infection in a live-virus assay, by disruption of gp41 (the crucial c-terminal sequence responsible for enabling fusion of... Published: 4/4/2019   |   Inventor(s): Brian Mcnaughton, Alan Kennan, Susanne Walker, Rachel Tennyson, Alex Chapman Keywords(s):   Category(s): Human Health, Biotechnology

Split-Supercharged GFP: A Robust Platform to Detect Protein-Protein Interactions Patent Status: US Patent Issued, PCT Patent PendingFeatures and Benefits• Rapid detection of polypeptide interactions inside E. coli• High signal-to-noise• Efficient peptide-peptide interaction detection at physiological temperature• Detection of interactions involving aggregation-prone polypeptides Split-supercharged... Published: 11/8/2018   |   Inventor(s): Brian Mcnaughton, Brett Blakeley, Alex Chapman Keywords(s):   Category(s): Biotechnology, Chemicals & Materials, Other Innovations