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Nickel-Catalyzed C-N Cross-Coupling via Direct Photoexcitation of Nickel-Amine Complexes
Mild Nickel-Catalyzing Cross-Coupling MethodologyC-N Cross-Coupling via Photoexcitation of Nickel-Amine Complexes At a GlanceWe introduce a carbon-nitrogen (C-N) cross-coupling method that operates at room temperature using an inexpensive nickel (Ni) source while being tolerant to oxygen and proceeds through direct irradiation of the Ni complex...
Published: 5/30/2019
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Inventor(s): Garret Miyake, Chern-Hooi Lim, Max Kudisch, Bin Liu
Keywords(s):
Category(s): Chemicals & Materials, Biotechnology
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Flexible multilayered pump for use as a ventricular assist device
At a Glance: This invention is essentially a ventricular assist device, made up of a flexible polymer involving prosthetic heart valves, hydraulic chambers and an artificial muscle, which will be used to help drive blood flow and are also used during heart failure. This invention is believed to result in fewer adverse outcomes for patients, such a...
Published: 4/4/2019
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Inventor(s): David Bark
Keywords(s):
Category(s): Biotechnology, Chemicals & Materials, Human Health
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Recyclable Biopolymers from Chemical Ring-Opening Polymerization of Five-Membered Heterocyclic Monomers by Basic Catalysts
Recyclable Biopolymers from Chemical Ring-Opening Polymerization of Five-Membered Heterocyclic Monomers by Basic CatalystsAt a Glance: The invention is the first effective organopolymerization of the biorenewable “non-polymerizable” gamma-butyrolactone (γ-BL) to high-molecular-weight metal-free recyclable polyester.The chemical synthesis...
Published: 4/4/2019
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Inventor(s): Eugene Chen, Miao Hong
Keywords(s):
Category(s): Chemicals & Materials, Energy & Natural Resources
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Chemical Synthesis of Poly(3-hydroxybutyrate) from Bio-Sourced Cyclic Diolides
At a Glance: The invention is a new chemical synthesis route to poly(3-hydroxybutyrate) from bio-sourced cyclic diolides Advantages include high isotacticity and molecular weight Commercial applications include biomaterials, biomedical applications, biodegradable polyester and biodegradable thermoplasticsBackground: Poly(hydroxyalkanoate)s (PHAs), naturally...
Published: 4/4/2019
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Inventor(s): Eugene Chen, Xiaoyan Tang
Keywords(s):
Category(s): Chemicals & Materials
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A Metal Reducing Enzymatic Tag for Optical and Electron Microscopy
At a Glance: ● A clonable maker for electron and optical microscopy. ● Allows for high resolution imaging using non-disruptive modalities● Can be readily adapted to flow cytometry● Potential to provide a platform for radio frequency interactions with a protein of interest.● Immediately applicable markets: academic research,...
Published: 4/4/2019
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Inventor(s): Christopher Ackerson, Zachary Butz, Richard Nemeth, Ryan Riskowski, Kanda Borgognoni
Keywords(s):
Category(s): Biotechnology, Chemicals & Materials, Electronic Devices & Instrumentation
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Recyclable and Robust Polyesters and Stereocomplexes Based on Ring-Fused γ-Butyrolactones
Plastics which can be Chemically Recycled Completely and Infinitely Inventors: Eugene Chen and Jian Bo-ZhuPatent status: Provisional Patent filed, pending conversionSummaryPetroleum-derived plastics are major pollutants and diminish our natural resources, while biomass-derived, industrially-compostable plastics are unable to be effectively recycled....
Published: 4/4/2019
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Inventor(s): Eugene Chen, Jian-Bo Zhu
Keywords(s):
Category(s): Chemicals & Materials
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Nanoparticle Diffusion Sampler with Direct Analysis
Nanoparticle sampling device for protection of nanomaterial-producing employeesInventor: Candace Su-Jung TsaiAt a Glance• Device directly measures airborne nanoparticles preventing harmful exposure for employees that produce nanomaterials• Current nanoparticle measuring devices are large, inefficient, and regularly miss detection...
Published: 4/4/2019
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Inventor(s): Su-Jung (Candace) Tsai
Keywords(s):
Category(s): Chemicals & Materials, Electronic Devices & Instrumentation
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Additive Manufacturing of Ceramic Nanopowder by Direct Coagulation Printing
At a GlanceResearchers at Colorado State University have created the first system capable of 3D printing ceramics without a binder, starting from a nanopowder, using a direct coagulation printing method, with an extrusion delivery system.AbstractTraditional manufacture of ceramics with subtractive methods is limited due to their hardness and brittleness,...
Published: 11/8/2018
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Inventor(s): Tucker Hensen, Troy Holland
Keywords(s):
Category(s): Chemicals & Materials
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Reversible interpenetrating polymer network
Inventors: Scott Compel, Andrea Wong, and Chris AckersonPatent status: US and PCT applications pendingInnovators at Colorado State University have developed a novel and highly modular reversible interpenetrating polymer network (IPN). When mixing specific compounds are mixed in water, hydrogen bonds form a 3D network between the polymers that results...
Published: 4/4/2019
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Inventor(s): William Compel, Christopher Ackerson, O Wong
Keywords(s):
Category(s): Chemicals & Materials
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HeX-Bond for molecular engineering, medicinal chemistry applications, materials chemistry, and biological or chemical engineering
Investigators at Colorado State University have discovered a new form of a non-covalent interaction, which is named a hydrogen bond enhanced halogen bond (or HeX-B, for short). The HeX-B was engineered into the enzyme lysozyme to increase the thermal stability of a commonly used enzyme by 1°C and the activity by 15% at elevated temperatures relative...
Published: 4/4/2019
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Inventor(s): Pui Shing Ho, Anna-Carin Carlsson, Matthew Scholfield, Melissa Ford, Rhianon Rowe Hartje, Austin Alexander, Ryan Mehl
Keywords(s):
Category(s): Biotechnology, Chemicals & Materials, Human Health
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